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Mechanism of Action Epithalon wird hinsichtlich seines Potenzials zur Aktivierung der Telomerase untersucht , eines Enzyms, das zur Aufrechterhaltung der Telomerlnge in sich teilenden Zellen beitrgt

Sirtuins, particularly SIRT1(Zhao et al., 2022b), are NAD-dependent deacetylases that regulate enzymes involved in fatty acid catabolism, such as AMPK, PPAR-, SREBP-1c, and Nrf2

This effect has been linked to the activation of NF E2-related factor 2 (Nrf2), a transcription factor that responds to OS by upregulating genes associated with antioxidant pathways, including those related to GSH synthesis and conjugation

10.1016/0925-4439(95)00091-7 Biochim Biophys Acta

Development of a gene transfer-based treatment for radiation-induced salivary hypofunction