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This specific arrangement of aromatic and hydroxyl groups in phenols is responsible for the wide-ranging biological activities of phenols, including strong antioxidant potential, metal ion chelation, and free-radical scavenging (Figure 2).[29] The classification and sources of phenolics [30] Phenolic compounds form a very heterogeneous group of metabolites that are produced by plants and are classified according to the number of aromatic rings, the presence of hydroxyl groups, and the characteristics of the side chain

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The extract effectively suppressed IgG2a, IgE, eosinophilia, and mucus hypersecretion and significantly inhibited the increase in mRNA expression and Th2-type cytokines, including IL-5 and IL-4 in lung tissue and bronchoalveolar lavage fluid (BALF) in the asthmatic mouse model

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Clinical trials show average weight reduction of 1522% of body weight over 68 weeks significantly beyond what diet and exercise alone typically produce for most patients