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Interestingly, this side effect was more common in individuals with darker baseline skin and in those who took many doses

In some cases, it can cause a temporary increase in blood pressure

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European Organization for Research and Treatment of Cancer Malignant Melanoma Cooperative Group Protocol 18832, the World Health Organization Melanoma Program Trial 15, and the North American Perfusion Group Southwest Oncology Group-8593

The indication is acquired and generalized hypoactive sexual desire disorder in premenopausal women