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La concentration plasmatique de GHK-Cu diminue significativement avec l'ge : d'environ 200 ng/mL l'ge de 20 ans, elle chute environ 80 ng/mL vers 60 ans

J Immunol (1999) 163(5):256875

A loss of function in the GST s classes ( M1 and T1 ) due to a structural deletion (Null mutation) impacts an individuals ability to detoxify genotoxic compounds [36, 37]