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In 1989, Lupron Depot TM , a controlled-release formulation for prostate cancer, became one of the first commercial products to use PLGA microspheres 113,114

Moreover, nanomaterials can distinguish cancer cells from normal tissues by recognizing their hypermetabolic characteristics or preventing ferroptosis in normal cells by activating antioxidant pathways

Educating patients, offering taste-masking strategies (like sugar-free gum or citrus), or adjusting the medication when appropriate can greatly improve outcomes

Heterodimerization of G-Protein-Coupled Receptors in the CNS