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which is particularly alarming since all antiretrovirals are used as part of drug mixtures, whereas a lot of studies on antiretroviral drugs toxicity in general report findings for individual drugs

doi: 10.3382/ps.2009-00117 153

S., Orr A

Immunity 40 , 91104 (2014)

While in many mammalian species UA is further degraded to allantoin, in humans and certain other primates the uricase activity responsible for this metabolic removal has been lost