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The highest Loewe score in Be(2)-C is 45.3 and reached at ~1800 nM MitoQ combined with ~10 nM DPI ( Figure 2B )

5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small molecule that inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that becomes overactive in metabolically aging tissue