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For microglia, after spinal cord injury (SCI), the concentration of lactate increases, triggering H4K12 lactylation, which is involved in the repair and functional recovery of spinal cord injury [137]

Aging naturally lowers production, while illnesses, infections, and certain medications speed up depletionmaking it vital to adopt habits that help preserve healthy levels

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Previous studies reported that berberine potentially treats inflammatory vascular injury by abolishing NLRP3 inflammasome activation via Ca 2+ signaling [112]