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So far, SDs have been predominantly described in paediatric cohorts, including long-term survivors of CO CP [127, 128], with a variable prevalence depending on the heterogeneous diagnostic tools used, ranging from self-assessment questionnaires of early works [127] to specific sleep-medicine tools in more recent reports [128, 129]

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Commonly, there was the recovery of the severe occlusion/occlusion-like syndrome, the recovery of multiorgan failure syndrome in the rats with vascular failure induced by major vessels occlusion, peripherally [18,19,20,21,22,23] and centrally [18,19,20,21,22,23,24,25,26,27,28,29,30], and other similar noxious procedures [18,19,20,21,22,23,24,25,26,27,28,29,30] that largely affect endothelium function, and multicausal pathology was fully recovered [18,19,20,21,22,23,24,25,26,27,28,29,30]

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