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The classic pencil-in-cup deformity, where the end of one bone erodes into a point and the adjacent bone cups around it, is pathognomonic for severe PsA

Imidacloprid degraded to 85% of its measured concentration between the onset and the end (day 21) of the toxicity test

Then pretreated HUVECs with QCT for 2 h and treated with Erastin for 1 h

10 Conclusions and future directions Female reproductive disorders remain a major global health challenge, with limited innovative therapeutic options, underscoring the urgent need for multi-target agents capable of addressing the intertwined endocrine, metabolic, inflammatory, and fibrotic pathways that drive disease progression