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Liu C, Liu X, Xiang X, Pang X, Chen S, Zhang Y, Ren E, Zhang L, Liu X, Lv P, Wang X, Luo W, Xia N, Chen X, Liu G

The gene has been identified in 1999 and annotated on chromosome 10 (Halestrap and Price, 1999)

Furthermore, the interplay between ferroptosis and other programmed cell death pathways (e.g., pyroptosis and necroptosis) in driving renal fibrosis is fragmented

A unifying feature is their ability to mitigate oxidative stressfor example, many flavonoids, alkaloids, and saponins activate the Nrf2/ARE pathway, upregulating endogenous antioxidant enzymes (such as superoxide dismutase and glutathione peroxidase) to neutralize excess reactive oxygen species (Wang Q

Carotenoids, including lutein, neoxanthin and -carotene, are important compounds found in broccoli that exhibit lipophilic antioxidant and immunomodulatory activities