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Similarly, we also consistently found a decreased presence of Iba1 + macrophages in B16-F10 metastatic tumors from CreERT2 mice (Supplementary Fig

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Through high-throughput screening approaches, large libraries of compounds can be screened against iPSC-derived cancer cells, leading to the identification of novel drug candidates and personalized treatment options [548, 586]

Lipid metabolism and lifespan Lipids are a diverse group of macromolecules, which not only serve as structural components of cellular membranes and as an important energy source, but are also recognized as important bioactive signaling molecules [54]