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Efficacy comparison : DBS significantly improves motor function and quality of life, particularly in patients with advanced disease and medication-refractory symptoms (Hacker et al., 2020

J Neuroinflammation 18:221

doi: 10.1128/AAC.01139-16 40 DalebrouxZDSvenssonSLGaynorECSwansonMS

Although OMV-DaFe (ferroptosis alone) achieved a tumor inhibition rate of approximately 60%, all treated mice died within 40 days

XA and Kyn only increased at a more pronounced deficiency suggesting that HK, KA and AA are more sensitive than XA and Kyn to vitamin B6 deficiency when the pathway is not stressed with tryptophan loading (183)