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Supplying Gclc KO mice with a high-fat diet (HFD) rescued the decreased triglyceride levels in the serum (Fig

However, the effective use of BLM in chemotherapy remains limited, as it precipitates dose-dependent interstitial pneumonia, resulting in pulmonary fibrosis in at least 10% of individuals treated with BLM, ultimately leading to irreversible lung structural damage (Yen et al., 2005

As research advances, PRLMs may provide a conceptual and translational bridge between understanding AD pathogenesis and developing precision-based interventions, laying the groundwork for future therapeutic breakthroughs