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Description

Ir J Med Sci 1994

Primul motiv este susinut de rezultatele cercetrilor pe oareci, care nu sunt relevante pentru om

The CPT1 subunit in the heart, skeletal muscle, and liver is inhibited by malonyl CoA [23], with heart and skeletal muscle being more sensitive to the regulation of this enzyme, and the brain-specific CPT1 subunit having a high affinity for malonyl CoA [24]

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Dietary intake also plays an important role in carnitine homeostasis of HD patients since the prevalence of malnutrition ranges from 18% to 75% of these cases [54]