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Yeast two-hybrid, BiFC, pull-down and Co-IP all validated the interaction between GCR1/2 and SlTOE1B in vitro and in vivo, and the C-terminus of GCR1/2 mainly interacted with SlTOE1B (Fig

demonstrated that MPH promotes ROS generation via activation of RAC1-dependent NADPH oxidase (NOX) and c-Src activation [149]

Findings indicate that the knockout of PTEN , a gene mutated in approximately 35% of GBM cases, reduced DNA repair protein RAD51 homolog 1 (RAD51) levels, leading to impaired HR