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Subsequently, they found that capsaicin can effectively inhibit the expression of vascular endothelial inflammatory mediators in both STZ-induced diabetic rats with diabetic retinopathy and human retinal microvascular endothelial cells exposed to high glucose

The lower ( FBXW7 , CSNK1A1 , and METTL14 ) or upper ( PLGRKT ) quartile expression from human patients was directly compared to the opposite quartile