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Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells

101-9, (2016) (PubMed)

Nat Genet (2010) 42(7):5705

Long-term fasting in humans has also been shown to induce a reductive shift in the blood acetoacetate/beta-hydroxybutyrate, indicative of the mitochondrial [NAD + ]/[NADH], representing a summed systemic redox change