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Before he became pope, he had served for a time as papal nuncio in Brussels and enjoyed the conversation and company of the cultured and easy-going aristocrats there

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Case 1 The patient was a 13-year-old boy who was born to consanguineous parents and was seen for fragility of the skin and mucous membranes that began at age 5 years with small erosions that formed on the hands and feet after minimal trauma, pain and bleeding of the gums, diarrhea, and intermittent constipation

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