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RNF4, an E3 Ubiquitin ligase, is pivotal for tumorigenesis in part by stabilizing oncoproteins and its role in DNA repair, thereby enhancing cancer cell survival and driving tumorigenesis

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In fact, it is also involved in the metabolism of amino acids and nucleic acids like folic acid, and it assists in synthesizing DNA, RNA, and fatty acids

Josephs University Medical Center, Paterson, NJ, USA Rajkumar Doshi Department of Health Policy and Management, Tabriz University of Medical Sciences, Tabriz, Iran Leila Doshmangir Department of Population Health Sciences, Kings College London, London, UK Abdel Douiri Department of Forensic Medicine and Toxicology, Manipal Academy of Higher Education, Mangalore, India Haneil Larson Dsouza, Prateek Rastogi, B