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FOXK1 can upregulate the transcription of glycolysis-related genes, regulate metabolic switching in renal tubular cells, and enhance glycolytic metabolism and fibrotic lesions [28]

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For example, Mn serves as the catalytic site in a wide range of enzymes, including SOD, glutamate synthetase, pyruvate carboxylase, arginase, hydrolase, phosphatases, transferases, dehydrogenases, kinases, peptidases, and decarboxylases

Microglia expresses some pattern recognition receptors that are engaged by pathogen-associated molecular patterns, triggering microglia activation

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