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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide 19 Purity (HPLC) >= 95%

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide 19 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine

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Description

19 Purity (HPLC) >= 95% Physical Appearance Dark Purple Solid Optical Properties Abs/Em Maxima: 555/585 nm Solubility DMSO

NCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

TCO (trans-cyclooctene) is a strained alkene used in click chemistry for bioorthogonal reactions like iEDDA (inverse electron-demand Diels-Alder)

RSC Chemical Biology

031 Purity (HPLC) >= 95% Solubility DMSO

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB dbco-maleimide 19 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine

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