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In light of this, we examine emerging therapeutic strategies aimed at reprogramming this axis, including pharmacological BA receptor modulation, microbiota-based interventions (e.g., engineered microbes, FMT, dietary strategies), and their synergistic potential with established cancer treatments like immune checkpoint inhibitors

2), which is a rate-limiting precursor for the synthesis of GSH

Islam T, Manna M, Reddy MK (2015) Glutathione peroxidase of Pennisetum glaucum (PgGPx) is a functional Cd2+ dependent peroxiredoxin that enhances tolerance against salinity and drought stress

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These results suggest the involvement of distinct brain pathways or systems, each modulated differently by the pharmacological association