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Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism

showed that markers of an impaired barrier function associated with bacterial translocation as LPS and LBP are increased in the serum of CD patients with active and inactive disease whereas they are only increased in UC patients with active disease

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[DOI] [PubMed] [Google Scholar] Suzuki M., Nagai Y., Wada K., Koike T

Although many studies have shown that the activation of INH depends on high-valent (ferryl) heme in KatG, the confirmed binding site of INH within KatG has not been identified to date