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Additionally, the complex instigated the oligomerization of lipoylated proteins and the loss of Fe-S cluster proteins, consistent with characteristics of cuproptosis

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suggested that elevated copper and ceruloplasmin levels in NOSA-positive subjects might indicate increased cardiovascular risk [11]

The one human trial that will measure tolerability directly has not started reporting it is only recruiting (planned 2026), studies a topical gel on small standardized wounds , and lists safety as a secondary, not primary, outcome (NCT07437586)

Update on therapies for sarcopenia: novel approaches for age-related muscle wasting and weakness