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[40] induced the apoptosis of mouse pulmonary vascular endothelial cells with the intraperitoneal injection of CSE in 2009, also successfully establishing a mouse emphysema model, which provided a powerful guide for future research

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Although this mechanism could not be tested directly in the present study because body mass index data were largely unavailable, it offers a plausible partial explanation for the divergent findings between the two former-smoker subgroups that does not require invoking a direct antihypertensive effect of e-cigarette use

Several long-term (1 year) smoking-cessation trials and observational studies have shown the beneficial effects of increasing physical activities on mitigating weight gain after quitting

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