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The mechanism of LCH pathogenesis is unclear, although there is some evidence that the characteristic proliferation of Langerhans cells represents an abnormal immune reaction, possibly directed at the components of cigarette smoke [12, 13]

Then, we can try to understand if there are things we can do to intervene and prevent chronic smokers from developing this condition. Cheryl Blaha, Penn State College of Medicine

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doi: 10.1038/s41557-024-01714-7 85 IyerR

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