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coli strains used originated or were derived from the KEIO collection (Baba et al., 2006), and were routinely cultivated at 37 C in Luria-Bertani (LB) medium, supplemented with antibiotics when required for plasmid maintenance and marker selection (ampicillin 200 g/mL or kanamycin 100 g/mL), if not stated differently

In the cell, NADPH is at high concentrations, and NADP + is at low concentrations

However, the pathogenesis of AD is much more complex and oxidative stress may play a patho-physiological role (Sultana and Butterfield 2010)

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Funding This work was funded by the Natural Sciences and Engineering Research Council of Canada (NSERC, Discovery grant nos