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Analysis Chi-squared tests were mostly used to assess differences across study groups, with Mann-Whitney U tests used for labeling outcomes given their non-normal distributions

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When there is an absence of evidence to provide confidence that there is benefit from implementing a new prevention service or when a conclusion of possible benefit requires a high level of speculation on linkages of uncertain evidence, but there is high certainty that some patients would be harmed or scarce health care resources expended, the task force may make a strong recommendation against service implementation

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