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The history of tobacco use in the Americas goes back over 1,000 years when natives of the region chewed or smoked the leaves of the plant now known as Nicotiana rustica (primarily in the north) and Nicotiana tabacum (mostly in the south)

We created a dichotomous variable that indicates whether the mother took steps to quit smoking during pregnancy

The invention of the Bonsack machine in 1881 revolutionized the tobacco industry by allowing for the automated production of cigarettes, resulting in a significant increase in the speed and efficiency of production

doi:10.1016/S0376-8716(99)00034-4

Academic Press, New York, NY