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Can Smoking Cause Constipation? Surprised? While smoking itself isn't a direct cause of constipation, nicotine can mess with your gut motility . When you quit smoking, your bowels may temporarily Smoking and IBS: What Does the Research Say? Nicotine and Digestion: Does Nicotine Make You Poop? GoodRx Frequency and severity of irritable bowel syndrome in cigarette smokers, Turkey 2019 As a doctor, I hear this more than you'd think: I can't quit smoking because I can't poop without it. This is a real, physiological response, not an excuse. Here's the science

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