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Acknowledgments The authors would like to thank Andrea Puglisi for producing the figure in this manuscript

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Oral submucous fibrosis OSF is a chronic, insidious disease that affects the submucosa of the oral cavity resulting in progressive limitation of mouth opening which is a hallmark feature of this disease18

Wiesbaden: Harrassowitz

There is clearly inter-individual variability in the way smokers regulate their nicotine intake per cigarette, with increasing frequency in a natural setting and in attempting to quit, the researchers wrote