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Those references rely on outdated historical narratives

These include viral or bacterial single-stranded RNAs (ssRNAs) rich in guanine (G) or uracil (U), double-stranded siRNAs, microRNAs, and endogenous RNAs released from necrotic cells, as well as nucleosides, nucleoside analogues (e.g., loxoribine), and oligonucleotides within endosomal compartments [229]

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This is where the esophagus becomes inflamed, and the muscles used to swallow become weak