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Consequently, further exploration is necessary to elucidate the molecular correlation between the dynamic changes of glutamine metabolism, a pivotal metabolic pathway within the tumor microenvironment, and the extent of T-lymphocyte activation

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The term NAFLD was first introduced in 1980 to characterize the clinical presentation of steatohepatitis, a severe liver injury characterized by lobular inflammation, steatosis, and ballooning degeneration of hepatocytes in patients with obesity and other metabolic disorders who did not consume alcohol [15]

Del Giglio A, Drach J, Kornblau SM, Patel S, Novaes M, Khetan R, Sawaya N, Dorlhiac-Llacer P, Chamone DF, Andreeff M , et al

Lysosomal exocytosis Lysosomal exocytosis refers to the mechanism through which lysosomes are discharged from within the cellular milieu and transported to the extracellular space