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6e) and a higher M3-lactate/M2-citrate ratio in the mutant cells (Fig

According to previous studies by Park et al (121) and Lee et al (122), terrein, a novel fungal metabolite reduces TYR expression by downregulating MITF in a manner that is dependent on ERK activation, with its inhibitory effects on melanin synthesis prolonged by ubiquitin-mediated proteasomal degradation