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T cells have been shown to incorporate BHBderived acetylCoA into the TCA cycle (Zhang et al , 2020)

Investigators and centers maintained emergency sealed opaque envelopes for each numbered drug, containing the randomization code for a given patient, for emergency unblinding only in the event of a serious life-threatening adverse event

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In summary, we found that KG was required for histone acetylation via TMHLE-catalyzed carnitine synthesis to facilitate HR-mediated DNA repair in CCNE1-driven models