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References Abo El Fotoh W.M.M., et al

So one of the primary functions of histamines is to cause something called a vasodilation

It is important to note that B12 levels should ideally be measured before commencing replacement therapy, as supplementation rapidly normalises biochemical markers, potentially obscuring the diagnosis

These changes lead to altered oxidative phosphorylation, as well as increased oxidative stress, calcium influx, inflammation, apoptosis, and mitochondrial dysfunction, being all of them physiopathological processes commonly observed in aging and its associated diseases (McCully, 2018)