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The structural and conformational information of most members of SLC family including DAT was obtained from the bacterial leucine transporter (LeuT) which has high sequence similarity to the eukaryotic SLC6 transporters (Penmatsa and Gouaux, 2014

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Its ability to stimulate gastric acid secretion and regulate various aspects of gastrointestinal function has made it a valuable tool in both basic research and clinical practice

Discussion Cellular senescence, triggered by diverse external and internal stressors, serves as a protective response that prevents the proliferation of impaired cells, thereby conferring resistance to cancer 45,468