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Specifically, PYC improves endothelial function, microcirculation, and inflammatory marker profiles in patients recovering from symptomatic coronavirus disease-2019 (COVID-19) ( Given the increasing threat of emerging and re-emerging viral infections ( 2 Antioxidative effects of PYC PYC exhibits potent antioxidant properties by effectively scavenging reactive oxygen and nitrogen speciesincluding superoxide (O 2 ), nitric oxide (NO), peroxynitrite (ONOO ), and hydroxyl radicals (OH)thereby counteracting oxidative stress induced by excessive reactive oxygen species (ROS) production ( Following sepsis induction in Wistar albino rats, PYC treatment decreased malondialdehyde levels, increased GSH levels, and enhanced SOD and GPx activities

A fundamental unresolved issue concerns whether mitochondrial dysfunction acts as a primary initiator or merely an amplifier of pulmonary inflammation

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doi: 10.1155/2022/2485959, [DOI] [PMC free article] [PubMed] [Google Scholar] 186.Wang M, Su S, Jiang S, Sun X, Wang J