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Because polyploidy is not a feature of R11 cells, it is tempting to speculate that cancer-related genetic changes render cytokinesis in U251 cells susceptible to disruptions of Aurora-A activity, thereby resulting in polyploidisation over cellular generations

discussion 1621-1612

Oral carnitine supplementation reduces body weight and insulin resistance in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial