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The treatment of sodium selenite was reported to increase GLP-1R, IRS-1, and preproinsulin mRNA both at transcriptional and translational levels in the liver of diabetic rats[172]

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( Apoplast ascorbate levels and expression of ascorbate oxidase A substantial portion of cellular AsA (almost 90%) is reported to be localized in the cytoplasm, however, in apoplast its concentration is reported in milli-molar range due to its export from the cytosol (Pignocchi et al., 2003