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146 With SGLT2i administration, proposed mechanisms that alter the insulin:glucagon ratio include loss of paracrine inhibition by insulin during euglycaemia, resulting in increased endogenous glucose production, increased glucagon secretion, reduced tissue glucose disposal, insulinopenia and elevations in plasma cortisol and catecholamines (Figure 16)

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ber die Nutzung dieses Dienstes wird Ihnen unser Standort angezeigt und eine etwaige Anfahrt erleichtert