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doi:10.1016/j.neubiorev.2010.10.001 Berk M, Dean O, Cotton SM, Gama CS, Kapczinski F, Fernandes BS, Kohlmann K, Jeavons S, Hewitt K, Allwang C, Cobb H, Bush AI, Schapkaitz I, Dodd S, Malhi GS (2011b) The efficacy of N -acetylcysteine as an adjunctive treatment in bipolar depression: an open label trial