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Description

and Phenylalanine, Methylfolate and S-Adenosyl-Methionine (SAMe) for neurotransmitter and dopamine support

Because Arg67 is the ligand that directly interacts with MDSA, the R67A mutant demonstrated activity that was notably less inhibited by MDSA, with an IC 50 value of 185 M, which was over 300-fold that of the WT (Table 1)