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Ample evidence exists that all these conditionscardiovascular risk factors, metabolic syndrome, insulin resistance, increased oxidative stress and systemic inflammation are great promoters of CVD and CVD-related mortality

High levels of oxidative stress can lead to inflammatory conditions (diabetes, cardiovascular disease and autoimmune disease) and illnesses such as cancer

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Fewer amino acids mean fewer potential degradation sites and simpler folding that is more resistant to thermal denaturation

Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons