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Researchers continue to study how the drug may be combined with other therapies for positive patient outcomes

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Dose reduction should be done gradually and should be done under medical surveillance

Replacing the Estimated Allowed Amount With the Median Allowed Amount and Adding the 10th and the 90th Percentile Allowed Amounts In the CY 2026 OPPS/ASC proposed rule (90 FR 33476), we proposed to revise 180.50(b)(2)(ii)(C) to require, at new 180.50(b)(2)(ii)(C)( 2 ), that, beginning January 1, 2026, if a payer-specific negotiated charge is based on a percentage or algorithm, the hospital must calculate and encode the median allowed amount in dollars for that item or service