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GGsTop ATTENUATES IL-13 INDUCED AIRWAY HYPER-REACTIVITY Treatment of mouse lung with IL-13 caused a significant, and dose dependent increase in relative airway resistance following methacholine challenge compared to saline treated control mice ( Figure 2 )

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Subcutaneous injection means the dose is delivered just under the skin with a fine needle, a route commonly used for peptide protocols because it allows steady, self-managed dosing

Drug library screening identified several promising radioprotective compounds The glutathione and senescence assays were used to screen a library of FDA-approved drugs (Selleck Chemicals) at 100 M

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