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In addition, VGB4 inhibited VEGF-A-induced sprouting angiogenesis in collagen matrix with the maximum reduction effect on sprout number by 67.5% and 84.1% at 0.55 M and 0.74 M, respectively, as compared to control and scr ( P 0.001) (Fig

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All these parameters may contribute to explain the lack of reproducibility between studies, and standardizing data records may help alleviate this issue in future studies