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Table 1 Multi-targeted mechanisms of hepatoprotection

10.1007/s40200-022-01053-9 118 ZhangB.ChenX.RuF.GanY.LiB.XiaW.et al (2021)

Some studies in rodents have added KYNA at massive doses (well over 100 mg/kg, getting into the millimolar range in serum/plasma), seemingly without ill effects (indeed sometimes with protective effects)