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a After administration of 100 Ci of iodine ( 131 I)

Metabonomic and transcriptomics analysis showed that branched chain amino acid degradation, glycine synthesis, and glutamine metabolism pathways were significantly dysregulated in fatty liver, interacting with fatty acid metabolism and exacerbating liver lipid accumulation [45,46,47]

Major nerve injury is rare Injury to the larger motor nerves is rare and sits mostly in case reports rather than routine series, and where it has been described, it has tended to follow overly aggressive surgery such as over-resection of skin (3)

In addition, melatonin protects against ferroptosis by reducing the expression of the H2O2-producing LOX enzymes [414, 418] and has the potential to do so by reducing the expression of the H2O2-producing NOX enzymes [419,420,421,422]

RESULTS Reduced protein-SSG is associated with decreased glutathione pools by CHAC1 induction in multiple cell types undergoing ferroptosis To investigate the pattern of protein-SSG in ferroptotic cells, we used the classical and commonly used ferroptosis inducer erastin because it can extensively induce ferroptosis in cells